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A GP or specialist can assess underlying health conditions that may increase the risk of adverse effects and can advise on licensed, evidence-based alternatives available through NHS or private prescribing pathways

Tryptophan increased serum 5-HT levels, enhanced brain BDNF expression, reduced neuroinflammation, improved mitochondrial energy metabolism and restored gut barrier integrity by upregulating tight junction proteins (Weng et al., 2024

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