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These are best treated as auxiliary hypotheses rather than primary mechanism, as the experimental support is narrower than for the VEGFR2-eNOS axis
BPC-157 has substantial published research, primarily preclinical

Patients (or caregivers) use them to self-administer insulin at home or in clinics, usually injecting into fatty areas like the abdomen, thigh, buttock or upper arm

PMID: 10387962
