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Host-derived antioxidants are essential to suppress carcinogenesis or cancer initiation

Information for Patients, Pregnancy]

Nature communications 2017;8, 15691, doi:10.1038/ncomms15691

Abbreviations APCs: Antigen-Presenting Cells BALF: Bronchoalveolar Lavage Fluid COPD: Chronic Obstructive Pulmonary Disease COX-2: Cyclooxygenase-2 DNA: Deoxyribonucleic Acid EGF: Epidermal Growth Factor F: Female FEV1: Forced Expiratory Volume in 1 s FOXP3: Forkhead Box Protein 3 GSH: Glutathione hs-CRP: High-sensitivity C-reactive protein iNOS: Inducible Nitric Oxide Synthase IL: Interleukin ILCs: Innate Lymphoid Cells JAK: Janus Kinase M: Male MDA: Malondialdehyde NF-B: Nuclear Factor-kappa B NO: Nitric Oxide NOS: Nitric Oxide Synthase OVA: Ovalbumin PEF: Peak Expiratory Flow PDGF: Platelet-Derived Growth Factor PPAR: Peroxisome Proliferator-Activated Receptor PFT: Pulmonary Function Test ROS: Reactive Oxygen Species RNS: Reactive Nitrogen Species SOD: Superoxide Dismutase STAT: Signal Transducer and Activator of Transcription TGF-: Transforming Growth Factor-beta Th: T-helper cell TLRs: Toll-like Receptors TNF-: Tumor Necrosis Factor-alpha TSLP: Thymic Stromal Lymphopoietin WBC: White Blood Cell References Hough KP, Curtiss ML, Blain TJ, Liu RM, Trevor J, Deshane JS, et al

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