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Adequate B12 levels can help preserve the health and integrity of the nervous system, promoting optimal nerve transmission and reducing the risk of neurological disorders
The next paragraphs will discuss genetic predisposition and susceptibility as an underlying risk factor for ME/CFS - the superimposition of external stressors and exposures (59) results in a state of aberrant homeostasis, where a temporary homeostatic state of functioning occurs, but functions at a less optimum level (64)

I have many patients who feel so great with B12 shots they simply continue taking them each week regardless of what their labs show

B vitamins are consumed at higher rates during intense exercise due to their central role in energy metabolism and tissue repair

This applies to both compounds, but it is especially critical for tirzepatide where dose escalation directly impacts GI tolerability

Month 3+: Long-term remodeling
