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The method of administration and its duration are determined by the cause of the deficiency and the established therapeutic target [5,6]

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*Journal of Pharmacological and Toxicological Methods*, 70(1), 1-17

Like its better-known relative GHK-Cu (Glycyl-Histidyl-Lysine copper), AHK-Cu is a tripeptide three amino acids bonded in sequence with a copper(II) ion coordinated to the peptide backbone

Medication use , particularly long-term metformin therapy, proton pump inhibitors, and H2-receptor antagonists, increases deficiency risk