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Gomes WJ, Dayan V, Myers PO, Almeida R, Puskas JD, Taggart DP, Arai H, Ono M et al (2023) The 2021 American College of Cardiology/American Heart Association/Society for Cardiac Angiography and Interventions guideline for coronary artery revascularization

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In this extended arrangement, the EGFR-binding domain has more spatial freedom to adopt an optimal orientation, enabling simultaneous and efficient engagement with both EGFR and HER2 with minimal steric hindrance