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However, their modest efficacy in slowing GA lesion growth without demonstrating clear functional benefit, the burden of monthly or bi-monthly intravitreal injections, and potential safety concerns, including an increased risk of conversion to neovascular AMD, have limited their clinical use and precluded regulatory approval in Europe

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35,36,37 Low methionine concentration can also lead to cell morphological changes and cell proliferation

Modulation of beta-amyloid aggregation using ascorbic acid