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Anti-inflammation NF-kB pathway inhibition and reduced pro-inflammatory mediator production in keratitis and colitis models

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A 2017, 121 , 699 707, DOI: 10.1021/acs.jpca.6b1099051Prediction of pKa Values for Druglike Molecules Using Semiempirical Quantum Chemical MethodsJensen, Jan H

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injection of 50 mg/kg sodium pentobarbital (Sigma), and thoracic aorta was carefully dissected and maintained at 37 C in Krebs solution containing 118.2 mM NaCl, 4.7 mM KCl, 1.2 mM MgSO 4 , 25 mM NaHCO 3 , 1.2 mM KH 2 PO 4 , 1.9 mM CaCl 2 and 11.7 mM dextrose (pH 7.4, 95% O 2 , 5% CO 2 )

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