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[DOI] [PubMed] [Google Scholar] 10.Yeargin-Allsopp M, Rice C, Karapurkar T, Doernberg N, Boyle C, Murphy C

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Despite these protective mechanisms, elevated serum B12 levels (hypercobalaminaemia) can occur and may indicate underlying health conditions rather than simple overconsumption

Despite the added advantages of the freeze-drying method, there are a few disadvantages associated with it such as membrane integrity may be lost, encapsulated substances might leak out from the vesicle and vesicle size might decrease [163]