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Notably, some nanomaterials can themselves activate NLRP3 in the CNS [198], underscoring the need for careful nanoengineering and mechanistic evaluation
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The authors demonstrated that following intranasal administration, circSCMH1@LNP1 enters the olfactory bulb via olfactory nerves and subsequently distributes to other brain regions
The deeper question is how quickly will they move from gym conversations and become routines
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The non-invasive cell entry mechanism of protamine is a key advantage, which avoids damage to the cell membrane [151]
