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[DOI] [PMC free article] [PubMed] [Google Scholar] 241.Ilic S., Drmic D., Franjic S., Kolenc D., Coric M., Brcic L., Klicek R., Radic B., Sever M., Djuzel V., et al

Prevalence is greatest in young adults and in seniors

Animal studies have not reported major toxicity, but the lack of comprehensive human data means risks are unknown467

Supplemental Se may also promote inhibition of cell growth and apoptosis by multiple mechanisms, including the enhanced accumulation of Se-metabolites that could be toxic to cells (75, 303)

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Why experts are watching: NAD+ is everywhere in the longevity conversation, but the focus is shifting from merely topping off levels to stopping the leak