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It should be noted that the in vivo HO concentration was calculated using the in vitro HO sensing curve as the calibration curve to convert the signal into concentration

[DOI] [PMC free article] [PubMed] [Google Scholar] BenitesZapata, V

The ligand GSH molecules in holo Grxs are unstable and can be exchanged with free GSH, which inhibits the FeS cluster transfer from holo Grxs to apo Fdx

Meanwhile, ginsenoside Rg3 significantly increased glutathione S-transferase 2 (GSTA2) protein expressionand activated the transcription of GSTA2 downstream of multiple cellular signaling pathways, including protein kinase A (PKA), PI3K and JNK (Gum and Cho, 2013b)

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