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DPD inhibition, on the other hand, has been shown to re-sensitize CRC to 5-FU both in vitro and in vivo , indicating that interference of DPD could be an approach to overcome 5-FU resistance (Zhang et al., 2020)
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Interestingly, not only neural-produced IGF-I is involved in these processes
These designations are intended to help readers assess the strength of the evidence supporting the use of specific interventions or approaches
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