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131 However, 24-day intravenous infusion of SAM did not affect the size of the formed tumors, which may be due to the compensatory induction of GNMT, and prevented SAM accumulation

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Despite the first publication of this finding by Kuzminski in 1998, (5) a survey of Canadian physicians in 2007 revealed that 5.6% used oral vitamin B12 as an alternative to intramuscular injections and that only 25% of physicians were aware of the published trial