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Additionally, members of the ABC-transporter family, endosomal vesicular transport proteins as well as components of HOPS complex and endolysosomal fusion proteins were demonstrated to be involved in LRO biogenesis and function independently of endosome-lysosome fusion and apoptotic clearance 12,13,14,17

(Albin 2022) [#2] Maintenance dose : Starting dose is generally 1.66-2.33 PE/kg IV q8hr (e.g., ~100 mg IV q8hr)

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doi: 10.1126/sciadv.1600200 163 MateoJBoysenGBarbieriCEBryantHECastroENelsonPSet al

Regulation of Impaired Angiogenesis in Diabetic Dermal Wound Healing by microRNA-26a