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12.9%, adjusted HR [aHR]: 0.57, 95% CI 0.51, 0.64), MACE (14.8% vs

184,185,186,187 Interactions with other pathways GLP-1 not only promotes the release of insulin but also enhances the response of pancreatic -cells to insulin through the PI3K/Akt pathway, thereby improving insulin signal transduction and increasing the sensitivity of peripheral tissues to insulin

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