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The cytosolic level of acetyl-coA is regulated by phosphorylation of acetyl-CoA carboxylase Acc1 by Snf1/AMPK kinase, which inactivates the enzyme and limits the production of malonyl-coA from acetyl-coA and CO 2 , resulting in higher levels of acetyl-coA (Zhang, Galdieri and Vancura 2013)