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(1997) Effect of aging on the chaperone-like function of human alpha-crystallin assessed by three methods, Biochem

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Interestingly, in the context of SARS-CoV-2 infection, alterations in lipid metabolism and the xc-GSH-GPX4 axis, pivotal mechanisms of ferroptosis, are involved [231, 232], and further components of this mechanism, such as TfR1 and mGluR2, are crucial for the virus's internalisation, making it a potential therapeutic target

When exposed to cisplatin or 5-FU, GSDME +/+ mice experience significant intestinal damage and infiltration of immune cells
