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The expression of NRF1 is highest in skeletal muscle which is also the tissue that accounts for the largest percentage of glucose disposal in the body and, therefore, is the tissue that is most responsible for the hyperglycemia resulting from impaired insulin signaling

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This essential nutrient is crucial for red blood cell production, a healthy nervous system, and DNA synthesis

5g,h and Supplementary Video 9), supporting a role of kinesin-5 as a negative regulator of the process

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