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In addition, although macrophages work as a defense mechanism in a great range of infections, including virus infections, in SARS-CoV-2 infection it enables viral adhesion and anchoring to pulmonary parenquima and allows the virus to enter the organism through ACE2, as well as to replicate in their interior (Uversky et al

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Recombinant plasmids were transformed into TSINGKE DH5 Chemically Competent Cells (TSINGKE, China) and then Sanger sequenced by Sangon Biotech (Sangon, China)