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Moreover, due to modern agriculture, soils have become poorer in nutrients, resulting in conventionally grown foods containing fewer essential vitamins, minerals, and antioxidants

Rienks M, Carai P, van Teeffelen J, Eskens B, Verhesen W, Hemmeryckx B, Johnson DM, van Leeuwen R, Jones EA, Heymans S, Papageorgiou AP

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This is especially important for patients who have any GI-related problems: reflux/heartburn, SIBO/SIFO, chronic constipation, leaky gut, patients who are on acid blockers, etc

It also provides a protective antioxidant effect for nerve cells, limiting and preventing damage from unstable cells called oxidants

Often, once injections start, patients discontinue separate oral B supplements, sticking to perhaps just a basic multivitamin or prenatal vitamin at most