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However, the improvement of the histological markers suggests that the heart was successfully protected by the L-carnitine treatment

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In vivo , patient-derived xenografts (PDXs) and syngeneic mouse models have also demonstrated that CPEB3 depletion inhibits tumour growth and metastasis, as well as facilitating pharmacokinetics, bioavailability and lack of systemic toxicity evaluations prior to human testing which are invaluable safety and efficacy details (222)

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