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Tregs promote environment conversion from pro to anti-inflammatory by releasing anti-inflammatory cytokines (for example, IL-4, IL-10, IL-13) that stimulate M1 (bactericidal and inflammatory) to M2 (immunomodulatory) macrophages phenotype exchange, apoptosis or inhibition of neutrophil inflammatory activity (Li et al., 2018)

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Spatially restricted ROS production through photostimulation of matrix-KR was confirmed by comparing the responses of mitochondrial populations expressing microdomain-targeted HyPer7 as a function of distance from a single pulse of 561 nm at a fixed point (Fig

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