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J Inflam Bowel Dis Disor

the secretory products of glandular epithelial cells signal to the embryo and provide the fetus with nutrition during organogenesis ( A recent study linked accelerated cellular senescence in epithelial cells with inadequate endometrial development, a clinical condition known as thin endometrium that is associated with decreased clinical pregnancy and live birth rates

61 , e202206277 (2022)

Mechanistically, TSA suppressed inflammatory signaling by downregulating the activation of key proteins [toll-like receptor (TLR) 4, myeloid differentiation primary response 88 (MyD88) and NF-B] in the TLR4-MyD88-NF-B pathway (32)

Briefly, cells or tissues were collected and lysed in RIPA buffer containing 2% phosphatase and protease inhibitors (P1045, Beyotime, Shanghai, China)