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In addition, in vitro studies have found positive associations between homocysteine levels and proliferation, as well as oxidative damage in certain types of cancers, including breast cancer, which suggests its potential as a tumor marker for monitoring tumor activity (31,32)

[Google Scholar] Noctor G, Foyer CH

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Comparative metabolomic profiling of cystine-repleted or -starved NSCLC cells revealed that cystine-starved cells accumulate -glutamyl-di- or tripeptides, which were produced by non-canonical activity of GCLC

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DM2-OG, like ML226 treatment, had no consistent effects on histone marks in CD8 + T cells (Extended Data Fig