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Description
If there is neurological involvement, Cyanocobalamin may be given in doses of 1000 micrograms on alternate days and continued for as long as improvement occurs

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3D,E, Suppl

Distribution: Transcobalamin II appears to be involved in the rapid transport of the cobalamin to tissues

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Some sensitive patients may benefit from microdosing (below 0.25 mg) or customized compounded formulations to improve tolerance