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These are all growth-related molecules.[ref] Interleukin-1 (IL-1) is an inflammatory cytokine that can inhibit REST, which is a tumor suppressor

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Zanza C., Romenskaya T., Manetti A.C., Franceschi F., La Russa R., Bertozzi G., Maiese A., Savioli G., Volonnino G., Longhitano Y

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58 The decrease in autophagy in aged HSCs leads to the accumulation of active and healthy mitochondria and increased metabolism, particularly increased oxidative phosphorylation, promoting accelerated myeloid differentiation of HSCs