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Beyond defining a mitochondrial mechanism for fuel switching, this work provides a conceptual landscape for future investigation of metabolic adaptation across diverse physiological contexts, including exercise, distinct fasting paradigms, and hormone-driven metabolic regulation, and offers new insight into the determinants of responsiveness to GLP1R agonist-based anti-obesity therapies

Fontos szerepet jtszik az energiatermelsben azltal, hogy a zsrsavakat a sejt mitokondriumaiba szlltja

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The co-crystallized ligands were considered as the reference molecule to evaluate the binding mode of the drug molecules