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doi: 10.1038/cr.2009.139

Cyclodextrins may help improve drug transport through the membrane by forming inclusion complexes with active molecules, increasing bioavailability in the central nervous system
It should clearly state "U-100" or "for U-100 insulin." If it says anything else, do not use it

However, for B12, if any part of that complex digestive process is compromised especially the intrinsic factor or the absorption sites in the intestine then a significant portion of the B12 from a tablet might never reach your bloodstream

Chemically, vitamin B12 exists in several different forms

While results are promising, it has not yet received FDA approval for commercial use
