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The name originates from early research that identified the parent protein in gastric juice as having a protective and healing effect on the gastrointestinal tract and other tissues

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Pendlebury and Rothwell, 2021

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The glucagon arm is what distinguishes it from every GLP-1 and dual-agonist compound it increases energy expenditure in addition to the appetite and glycemic effects of the incretin receptors ( Coskun et al., Cell Metab 2022 )

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