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(78) previously established that heat shock protein beta-1 (HSPB1) is a negative regulator of ferroptosis in cancer cells

Niacin-supplemented AD mice also had elevated expression of genes including Ctnnb1 , Mdm2 , and Pten , which are involved in processes such as Wnt signalling, posttranslational modifications, and regulation of mTOR signalling [155]

Compared to Supersomes, human S9 and hepatocyte-based assays showed slightly improved metabolite coverage with human liver microsomes providing the closest representation of human in vivo amide hydrolysis (differing from in vivo metabolism in the cases of acetanilide, paracetamol and lidocaine)

SY: Writing original draft, Writing review & editing

We further discuss the structural changes of blood-brain barrier that correlates with Alzheimer's disease astrocyte

Rep 78 , 173193 (2026)
