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NRC, 1989)

Mechanistic studies suggest that certain natural products and isolated compounds can enhance lipid metabolism and reduce inflammation and fibrosis through pathways including PPAR/INSIG/SREBP1c and the transforming growth factor- (TGF-)/Smad/mitogen-activated protein kinase (MAPK) signaling pathway (Wu et al., 2019)

Schroer KT, Biagini Myers JM, Ryan PH, LeMasters GK, Bernstein DI, Villareal M, et al

The nervous system rapidly regulates organ interactions through pathways such as the vagus nerve, 17,18 whereas the endocrine system transmits information across multiple organs via hormonal signals such as insulin and cortisol

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