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REFERENCES New England Medical Journal, "A Massive Outbreak in Milwaukee of Cryptosporidium Infection Transmitted Through the Public Water Supply." William R

Both have distinct yet complementary mechanisms that, when combined, may offer synergistic benefits

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This guidance highlights selection of a minimal anticipated biological effect level, as this is becoming increasingly important as more targeted therapies are being developed that are very specific and potent with predicted pharmacologically active doses well below a dose that is thought to be safe based on the NOAEL.11 Table 2

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