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Phase 1 study of glutaminase (GLS) inhibitor CB-839 combined with either everolimus (E) or cabozantinib (Cabo) in patients (pts) with clear cell (cc) and papillary (pap) metastatic renal cell cancer (mRCC)

Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author/s

doi: 10.3389/fimmu.2021.652252 Received 12 January 2021 Accepted 31 August 2021 Published 23 September 2021 Volume 12 - 2021 Edited by Saurabh Chatterjee, University of South Carolina, United States Reviewed by Ayan Mondal, Stanford School of Medicine, United States

They are largely excreted out through feces and urine ( Metabolic regulation by gut microbiota Curcumin metabolism pathways in the intestinal and liver cells have been intensively studied

Toth CRA, et al

Effect of oral semaglutide compared with placebo and subcutaneous semaglutide on glycemic control in patients with type 2 diabetes: a randomized clinical trial