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During aging, the iron that accumulates in the retina, particularly in the choroid, retinal pigment epithelium (RPE), and photoreceptors [3,4,5], together with reduced intracellular antioxidant defenses, predisposes to oxidative stress-induced cell death

doi: 10.1016/j.lfs.2018.04.056

Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy, (in eng)

10.1038/sj.jcbfm.9600375 61 ZarkaM

These applications remain early-stage, but patients with a preventive mindset often include ReWire in a broader longevity stack alongside Cellular Longevity (Epithalon) and Better Vitality NAD+

10.1021/jf0114381 35 HuaX