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The internal relationship between ferroptosis and aseptic inflammation has been valued by increasing researchers and has provided a direction for unraveling the relationship between ferroptosis and DKD

(1) Controlled-Release PHEN/TPM in Severely Obese Adults (EQUIP) trial (obesity without comorbidities), (2) Controlled-Release Phentermine plus Topiramate Combination in Overweight and Obese Adults (CONQUER) trial (obesity with comorbidities), and (3) SEQUEL (2-year extension of CONQUER), were comprised of 7% of older adult participants across the trials, although the upper age limit was 70 [111,112,113]

Icotinib is approved for use as first-line monotherapy in patients with non-small-cell lung cancer with somatic EGFR mutations

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Examples of hydrogels currently in clinical trials but not yet approved by regulatory agencies are presented in Table 7(Tab