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Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF

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A divalent interaction between HPS1 and HPS4 is required for the formation of the biogenesis of lysosome-related organelle complex-3 (BLOC-3)

The functions of Rho and Ras GTPases exhibit distinct differences, as Rho GTPases are the main regulators of the actin cytoskeleton, while Ras primarily controls cell differentiation and proliferation, angiogenesis, and cell adhesion [30,98]

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This might have happened due to the very small number (three) of the subjects who were found to be slow during baseline