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However, a significant number of patients either do not respond to these treatments or eventually, these lose their effectiveness, indicating a need for alternative therapies (2)

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p = 0.049)

3d ) showed enhanced water solubility when formulated as its hydrochloride salt, which improved its potential for clinical applications

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Ring et al., 2014) Furthermore, cellular damage and increased paracellular permeability will increase the likelihood of microbial penetration into the intestinal tissue generating inflammation and other damage