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Lutein has been shown to provide protective actions against the toxicity and apoptosis caused by cigarette smoke extract in NHBE cells

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The prokineticin receptor antagonist PC1 downregulates macrophage activation markers, ameliorates structural damage in the PNS, prevents complete neuroimmune activation in the spinal cord, and mitigates BTZ-induced neurotoxicity (Moschetti et al., 2019)