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The evidence comes primarily from clinical practice reports and studies examining GLP-1 agonists combined with muscle-protective agents more broadly

This was in people with obesity, particularly at high doses

Originally, Semaglutide was developed and approved as a treatment for type 2 diabetes , where it demonstrated remarkable success in improving glycemic control and reducing the risk of cardiovascular complications

[16] Adverse GI effects reported during triamterene and/or hydrochlorothiazide therapy include abdominal pain, anorexia, appetite disturbance, dysgeusia, gastric irritation, cramps, constipation, nausea, vomiting, sialadenitis, xerostomia (dry mouth), and diarrhea

In one study, people lost an average of 4% of their weight in 16 weeks

Blood sugar changes If you have type 2 diabetes, stopping Ozempic will likely affect your blood glucose control