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These n-6 PUFAs are prone to peroxidation and have been implicated in promoting inflammation and cartilage degradation

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The glutaminase inhibitor CB-839 (telaglenastat) enhances the antimelanoma activity of T-cellmediated immunotherapies

First, it stimulates microglia to continue engulfing the hemoglobin that is released from blood cells, leading to the secretion of yet more iron ions, creating a positive feedback loop (64)