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Mice lacking Ndufs4 (Ndufs4KO) recapitulate several LS features, including difficulty to thrive, motor problems, breathing abnormalities, seizures, significantly shortened lifespan, neuroinflammation, and neurodegeneration 8,9,10

Phosphodiesterase-5 Inhibition Alleviates Pulmonary Hypertension and Basal Lamina Thickening in Rats Challenged by Chronic Hypoxia

Nat Genet 37(11):12341241

Mild side effectssuch as slight redness, swelling, or tenderness at the injection sitemay occur but typically resolve quickly

Cancer Epidemiology, Biomarkers and Prevention 5, 733748.Google Scholar Verhoeven, DTH, Assen, N, Goldbohm, RA, Dorant, E, vanVeer, P, Hermus, RJJ & van den Brandt, PA (1997a) Vitamin C and E, retinol, beta carotene and dietary fibre in relation to breast cancer risk: A prospective cohort study

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