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Research indicates that NNMT inhibition may promote fat loss, support insulin sensitivity and energy homeostasis, making 5-Amino-1MQ a promising tool for weight management and metabolic optimization

They're especially beneficial if you're feeling run down or have a known deficiency

doi:10.3390/antiox9050425 Gerdts J, Brace EJ, Sasaki Y, DiAntonio A, Milbrandt J

5-Amino-1MQ is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme overexpressed in obese fat tissue that depletes NAD+ precursors and SAM

The fragment does not bind the growth hormone receptor or activate the JAK2-STAT5 signaling pathway

by middle age, tissues may contain roughly half the NAD+ they had in youth