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The observed increase in HBV-DNA negative conversion rate in the observation group suggests that the combination therapy of reduced glutathione and entecavir may provide more sustained virological suppression

Liposomal oral formulations extend half-life 16.8-fold compared to native GSH, offering sustained release despite slower initial absorption

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Higher pH resulted in a lower critical concentration of NaCl necessary to elute CVA21 particles, similar to cation exchange chromatographic behavior (Figure 4A)