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Overall, this work should be regarded as a preliminary exploratory study that needs to be validated in larger independent cohorts

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Investigation of safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of a long-acting -msh analog in healthy overweight and obese subjects

Flutamide induces hepatic cell death and mitochondrial dysfunction via inhibition of Nrf2-mediated heme oxygenase-1