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l,6-Dimethyl-4-oxo-l,6,7,8,9,9a-hexahydro-4H-pyrido(l,2-a)-pyrimidine-3-caroxamide (CH-127) protects against the intestinal damage in rats caused by two weeks daily administration of indomethacin

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Nature 350 , 7781 (1991)

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Stroke Ischemic stroke is a leading cause of death and long term disability in the United States, 319 and patients who exhibit metabolic risk factors including diabetes mellitus, obesity and dyslipidemia are at a greater risk of experiencing stroke-related events