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Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are the two most common residual products of various cellular processes, including aerobic metabolism [37]

Am J Geriatr Pharmacother

in vitro with chemically reactive metabolites derived from several drugs displaying idiosyncratic toxicity, including troglitazone, acetaminophen, clozapine, and diclofenac (Okada et al., 2011

Shanmugam, V., Tsednee, M

Specific to the brain studies (both in vivo and in autopsy tissue) the region of interest (ROI) was noted

96 The major endogenous nonenzymatic low-molecular-mass antioxidants include N-acetylcysteine, glutathione, uric acid, melatonin, coenzyme Q and others