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Higher levels of the 16 pathways are associated with heavy periods, breast tenderness, breast cancer, obesity, hypothyroidism, pesticide toxicity (organochlorines), high omega-6 fatty acids, and inflammatory cytokines

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10.1039/D3BM00182B Biomaterials Sci
[DOI] [PubMed] [Google Scholar] 284.Rupp TL, Wesensten NJ, Bliese PD, Balkin TJ

Additionally, these copper changes corresponded to similar outcomes of perturbed functionality for key cuproenzymes, suggesting overlap related to altered copper processes
It can also rise for several different reasons, and those reasons do not carry the same level of risk
