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Specifically, studies have demonstrated that a functional SVCT2 is glycosylated 42 , causing it to shift from a 70 kDa native form to a higher molecular weight

These observations qualified the HepG2 model to study the mechanisms described herein

Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction

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It inhibits melanin transport and melanin-generating enzyme tyrosinase

However, much information may be gained from simple animal models that may be ultimately applied to mammals