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[9] High-dose niacin (used to treat cholesterol) lacks human safety data in pregnancy and could theoretically affect the fetus (for example, by causing hypotension or altering lipid metabolism)

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It is stable to autoclaving for short periods at 121C

"Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people"

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The compound has attracted significant interest in preclinical research for its effects on adipocyte metabolism, body composition, and muscle function in animal models